TAKE THE NINLARO® (IXAZOMIB) COMBINATION WHEREVER YOU GO

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What is the NINLARO treatment combination* dosing schedule?

The all-oral NINLARO treatment combination gives you some time back as well as for your loved ones and caregivers. With no travel to the clinic required for dosing of the all-oral NINLARO treatment combination*, NINLARO is taken just once a week for 3 weeks each month—at home, on the go, or wherever life takes you. NINLARO is taken along with 2 other oral medications, REVLIMID® (lenalidomide) and dexamethasone, as part of a three-pill combination, in 4-week cycles.

*NINLARO+lenalidomide+dexamethasone.

The NINLARO treatment combination for a 28-day cycle

The NINLARO® (ixazomib) treatment combination 28-day dosing schedule.

How should I take NINLARO?

Staying on top of your dosing schedule is key. The information in this section is based on how NINLARO was approved by the FDA. Please make sure to take the NINLARO treatment combination as prescribed by your healthcare provider.

NINLARO is different than other proteasome inhibitors because it is the first and only proteasome inhibitor that you can take on-the-go in capsule form. NINLARO is taken orally, so you don’t need to travel to a clinic or worry about scheduling extra appointments for injections or infusions. You still need to have your regular visits with your doctor.

NINLARO comes in a package that is different from other packaging you may have opened in the past. Get helpful step-by-step instructions for opening your NINLARO package.

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Take each dose of NINLARO at about the same time of day each week.

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Take each dose of NINLARO at least 1 hour before or at least 2 hours after food.

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Swallow NINLARO capsules whole with water. Do not crush, chew, or open the capsule.

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Do not take NINLARO at the same time as dexamethasone.

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Take NINLARO exactly as your healthcare provider tells you to take it.

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Your healthcare provider will do blood tests during treatment with NINLARO to check for side effects.

What if I miss a dose?

If you miss a dose of NINLARO, you can take the missed dose as long as the next scheduled one is more than 3 days away. NINLARO is absorbed into your body very quickly.

If you vomit after taking a dose of NINLARO, do not repeat the dose. Instead, take your next dose of NINLARO on the next scheduled day and time.

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What are some tips for staying on treatment?

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Partner with your care team

Even with the best intentions, it’s possible to miss doses of your treatment. You may be balancing dosing schedules, be concerned about side effects, or just forget because you’re human. Staying on therapy is about partnership. You and your healthcare team should work together to make decisions about your care. The goal is for you to have an understanding of, and control in, your treatment plan.

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Make every dose everyone's responsibility

The good news is that your healthcare team, caregivers, and loved ones can all help with adherence or taking all medications as prescribed by your healthcare provider. This way, the responsibility doesn't fall entirely on you. Talk with your care team about the importance of adherence and how you can work together to stay on treatment. When talking with your healthcare team specifically, consider the using the conversation starter to start thinking of questions to ask.

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Ask questions

Make sure that you fully understand your treatment and clarify anything that's confusing. Ask for information about potential side effects of treatment. Always talk to your doctor, as there are changes that can be made to your dose if you experience certain side effects.

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Remember to take your medication

Forgetting to take your medicine is a common reason for nonadherence. The important thing is that you are open with your care team and take steps to prevent it from happening.

How can I remember to take my medication?

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Build a routine and take your medication during a certain activity (eg, brushing your teeth, getting ready for the day)

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Keep track of doses you've taken by recording each one in a medication diary

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Set alarms (eg, watches, smartphones, text/call reminders)

What are some important things to remember when taking NINLARO?

  • For your safety, NINLARO has been sealed in a protective slipcase. You and your care team should keep NINLARO in this package until it's time to take your medication
     
  • Avoid direct contact with the capsule contents
     
  • If you accidentally get powder from the NINLARO capsule on your skin, wash the area well with soap and water
     
  • If you accidentally get powder from the NINLARO capsule in your eyes, flush your eyes well with water
     
  • Store NINLARO capsules in the original packaging until just before each use
     
  • Store NINLARO at room temperature. Do not store above 30°C (86°F)
     
  • Do not freeze NINLARO
     
  • Keep NINLARO and all medicines out of the reach of children

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