Man and woman embracing.

Everyone's journey is different

For 1 out of 3 people with multiple myeloma, their multiple myeloma returns for the first time with no or minimal symptoms. If this is your experience, finding out you're relapsing may feel unexpected, but it’s not unusual, and there are treatment options that may allow you to keep an active lifestyle for longer.  

Choosing the right next therapy when your multiple myeloma returns is key to helping you maintain an active lifestyle.

Everyone with multiple myeloma will have different journeys, but there are some common experiences that are shared by most people whose multiple myeloma has returned. It doesn’t matter if it’s after initial treatment or following many treatments, it’s important to understand the events that can occur.

Multiple myeloma returns

For most people, multiple myeloma will eventually return. When multiple myeloma has come back and can be detected by advanced lab tests and imaging, it is known as a relapse.

Refractory disease

Multiple myeloma may have never responded or may stop responding to a particular treatment.

Treatment reselection

Together, you and your healthcare provider will determine what the next multiple myeloma treatment is that makes sense for you.

Treatment response

A response is when myeloma cells decrease after treatment, which shows up as improvement in the laboratory tests that measure the disease, such as blood tests showing a decrease of M protein.

Side effects

You may experience side effects with treatment. Ask your doctor how to best manage any side effects that occur. Make sure to report any serious side effects as soon as you can.


Take all medications as prescribed by your healthcare provider and stay on top of your appointments. The success of your treatment depends on it.

Jennifer: when multiple myeloma comes back

“Don’t wait for someday—do the things that you love to do.”

—Jennifer, real patient

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VO: NINLARO is a prescription medicine used to treat multiple myeloma in combination with the medicines REVLIMID® (lenalidomide) and dexamethasone, in people who have received at least one prior treatment for their multiple myeloma.

NINLARO should not be used to treat the following people, unless they are participants in a controlled clinical trial:
• people who are receiving maintenance treatment, or
• people who have been newly diagnosed with multiple myeloma.

It is not known if NINLARO is safe and effective in children.

This video features a real patient sharing their experiences living with multiple myeloma and being treated with NINLARO, also called ixazomib. These experiences are based on the patient’s experiences at the time of recording. Given the nature of multiple myeloma, experiences may change over time.

This is Jennifer’s experiences while taking NINLARO, and yours may be different.

[No voiceover]

VO: Today we have the pleasure of hearing from Jennifer, a NINLARO Ambassador who will be sharing her experience with NINLARO and living with multiple myeloma.

VO: It is important to remember that everyone’s experience with multiple myeloma is unique and you should talk with your own doctor about your diagnosis and individual treatment plans.

VO: Now please welcome Jennifer!!

+++ 11:45:32 +++ Jennifer: When I was diagnosed with multiple myeloma, I didn't notice any symptoms, but my blood tests showed mild anemia and a blood protein level that had been slightly elevated. My doctor referred me to a hematologist oncologist for further testing to determine the cause. He ordered a series of tests, including a full-body X-ray, bone marrow biopsy, 24-hour urine analysis and

+++ 11:45:59 +++ several different blood tests.

+++ 11:41:47 +++ I remember sitting in the tiny windowless exam room with my oncologist after the results came in. He explained I had multiple myeloma. I knew I was gonna put up a fight, but I also knew there were no guarantees. Immediately after my diagnosis I went into high-gear problemsolving mode. I started reading everything I could about myeloma, and by doing so I became educated about my disease and its treatment.

+++ 11:42:20 +++ I also decided to set goals for myself based on the typical milestones my children would reach like graduations and weddings. I adopted the attitude that I still have a lot of living left to do. After some time on treatment, I hadn't achieved a complete remission, and my numbers crept up ever so slowly. I talked to my doctor about NINLARO, an oral medication treatment regimen for people with multiple myeloma who have received one prior treatment.

+++ 12:19:40 +++ I also knew I would be able to take it at home. My doctor and I discussed the risks and benefits with the NINLARO regimen, and together we decided to move forward. I responded well to treatment. Your experience may be different. I did have some neuropathy and fatigue. I discussed these side effects with my doctor, and he gave me a few tips on managing them.

+++ 11:53:55 +++ Jennifer: Today I'm spending as much time as I can with people who make me happy, and I'm doing things I enjoy. I'm much less likely to say I'll do something someday, because now I'm not sure what I'm waiting for. You only get one life, so live it. Don't wait for someday. Do the things that you love to do. Make every day count.

VO: Talk with your doctor to find out if NINLARO is a treatment option for you. Please stay tuned for the Important Safety Information for NINLARO.

VO: Important Safety Information for NINLARO NINLARO may cause serious side effects, including:

Low platelet counts (thrombocytopenia) are common with NINLARO and can sometimes be serious. You may need platelet transfusions if your counts are too low. Tell your healthcare provider if you have any signs of low platelet counts, including bleeding and easy bruising.

Stomach and intestinal (gastrointestinal) problems. Diarrhea, constipation, nausea, and vomiting are common with NINLARO and can sometimes be severe. Call your healthcare provider if you get any of these symptoms and they do not go away during treatment with NINLARO. Your healthcare provider may prescribe medicine to help treat your symptoms.

Nerve problems are common with NINLARO and may also be severe. Tell your healthcare provider if you get any new or worsening symptoms including: tingling, numbness, pain, a burning feeling in your feet or hands, or weakness in your arms or legs.

Swelling is common with NINLARO and can sometimes be severe. Tell your healthcare provider if you develop swelling in your arms, hands, legs, ankles, or feet, or if you gain weight from swelling.

Skin reactions. Rashes are common with NINLARO. NINLARO can cause rashes and other skin reactions that can be serious and can lead to death. Tell your healthcare provider right away if you get a new or worsening rash, severe blistering or peeling of the skin, or mouth sores.

Thrombotic microangiopathy (TMA). This is a condition involving blood clots and injury to small blood vessels that may cause harm to your kidneys, brain, and other organs, and may lead to death. Get medical help right away if you get any of the following signs or symptoms during treatment with NINLARO: fever, bruising, nose bleeds, tiredness, or decreased urination.

Liver problems. Tell your healthcare provider if you get these signs of a liver problem: yellowing of your skin or the whites of your eyes; pain in your right upper-stomach area.

Other common side effects of NINLARO include low white blood cell counts and bronchitis.

Tell your healthcare provider if you get new or worsening signs or symptoms of the following during treatment with NINLARO:
• skin rash and pain (shingles) due to reactivation of the chicken pox virus (herpes zoster)
• blurred vision or other changes in your vision, dry eye, and pink eye (conjunctivitis)

These are not all the possible side effects of NINLARO. Talk to your healthcare provider for medical advice about side effects. You may report side effects to Takeda at 1-844- 217-6468 or FDA at 1-800-FDA-1088. Before taking NINLARO, tell your healthcare provider about all your medical conditions, including if you:

• have liver problems.
• have kidney problems or are on dialysis.
• are pregnant or plan to become pregnant. NINLARO can harm your unborn baby.

Females who are able to become pregnant:
o Avoid becoming pregnant during treatment with NINLARO.
o Your healthcare provider will do a pregnancy test before you start treatment with NINLARO.
o You should use effective non-hormonal birth control during treatment and for 90 days after your last dose of NINLARO. If using hormonal contraceptives (for example, birth control pills), you should also use an additional barrier method of contraception (for example, diaphragm or condom). Talk to your healthcare provider about birth control methods that may be right for you during this time.

Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with NINLARO.

Males with female partners who are able to become pregnant:
o You should use effective birth control during treatment and for 90 days after your last dose of NINLARO.
o Tell your healthcare provider right away if your partner becomes pregnant or thinks she may be pregnant while you are being treated with NINLARO.
• are breastfeeding or plan to breastfeed. It is not known if NINLARO passes into breast milk, if it affects an infant who is breastfed, or breast milk production. Do not breastfeed during treatment with NINLARO and for 90 days after your last dose of NINLARO.

Taking too much NINLARO (overdose) can cause serious side effects, including death. If you take more NINLARO than instructed by your healthcare provider, call your healthcare provider right away or go to the nearest hospital emergency room right away. Take your medicine pack with you.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements or before starting any new medicines. Talk to your healthcare provider before starting any new medicines during treatment with NINLARO.

Please see Patient Information in the NINLARO (ixazomib) full Prescribing Information in the prescribing information tab on www.ninlaro.com.

Music Fade Out – No voiceover


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